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The Only ETF Targeting Generics

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Why Market Vectors® Generic Drugs ETF (GNRX), The Only ETF Targeting Generics? Industry may benefit from ongoing push to lower health care costs

Why Market Vectors® Generic Drugs ETF (GNRX), The Only ETF Targeting Generics?

Industry may benefit from ongoing push to lower health care costs

The only ETF offering global exposure to generic drug producers

Positioned to take advantage of the expected growth of biosimilars

• Approximately 60%1 of Americans take prescription drugs — 88%2 of these are generics
• Generics are shaping the future of pharma as demand continues to soar
• GNRX is the only ETF that gives investors access to the global generics industry

Market Vectors® Generic Drugs ETF (GNRX) seeks to replicate as closely as possible, before fees and expenses, the price and yield performance of the Indxx Global Generics & New Pharma Index (IGNRXT), which is intended to track the overall performance of companies that derive a significant proportion of their revenues or that have the potential to derive a significant proportion of their revenues from the generic drug industry, or that have a primary business focus on the generic drug industry.

Generic1

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Generic2

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Access Affordable Pharma

Across the globe more people than ever are taking prescription drugs, contributing to the rising costs of health care. Consumers, insurance companies, and governments are helping to fuel the growth of the generic drug industry as it often provides them with a lower cost alternative to brand name pharmaceuticals. Generics account for 88% of all prescriptions in the U.S.1, 55% in the EU2, and 47% in Japan3. With the Market Vectors Generic Drugs ETF (GNRX) investors can specifically target global generics manufacturers in their investment portfolios.

Generics Are Filling Medicine Cabinets Across the U.S.

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For illustrative purposes only. Percentages are approximations. Source: The Journal of American Medical Association, November 3, 2015. Generic Pharmaceutical Association 2015 Annual Savings Report.

Access Affordable Pharma

Generics account for 88% of prescriptions in the U.S. and 55% of prescriptions in the EU1.
Spending on pharmaceuticals worldwide is expected to increase to $1.3 trillion by 2018, 52% of this increase is expected to come from generics2. Global population growth, an aging demographic, and improved access to healthcare are expected to drive growth in both developed and emerging markets. Segment of Generic Prescriptions in the U.S.1
Over the past 10 years generic drug prescriptons in the U.S. have increased ~54%

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Recently generic drug makers have seen increased investor interest as many brand name drug makers lost patent protections (the “patent cliff”). The next stage of growth is expected to come from hard-to-copy biosimilars, biobetters and supergenerics as government policymakers and insurers continue to seek lower cost drug options for consumers.

Generics Defining the Future of Pharma

Increased global pharmaceutical spending and the drive for lower health care costs have supported demand for generics. Generic drug makers may also see new revenue opportunities from expiring patents on branded drugs and from new classes of generics, such as biosimilars, which provide the potential for higher margins.

Investment Case

The Only ETF Targeting Generics

Market Vectors Generic Drugs ETF (GNRX) is the only ETF specifically targeting the generic drug space by seeking to track an index of global generic drug manufacturers.

GNRX Details

Why GNRX?
• Approximately 60%1 of Americans take prescription drugs — 88%2 of these are generics
• Generics are shaping the future of pharma as demand continues to soar
• GNRX is the only ETF that gives investors access to the global generics industry

Generic6

Introduction to Generics and Biosimilars

https://youtube.com/watch?v=_5S5K4d4YVo

IMPORTANT DISCLOSURES

An investment in the Fund may be subject to risks which include, among others, the development, protection and exploitation of intellectual property rights, expiration of patents and inability to enforce intellectual property rights, significant costs associated with research and development and speculation that those investments will result in profitable products, arduous regulatory approval processes, rapid and significant technological change, uncertainty of reimbursement status by third-party payers such as Medicare, Medicaid, and private health insurance plans. Foreign and emerging markets investments are subject to risks, which include changes in economic and political conditions, foreign currency fluctuations, changes in foreign regulations, changes in currency exchange rates, unstable governments, and limited trading capacity which may make these investments volatile in price or difficult to trade. Medium-capitalization companies may be subject to elevated risks. The Fund’s assets may be concentrated in a particular sector and may be subject to more risk than investments in a diverse group of sectors.

Indxx Global Generics & New Pharma Index (the ”Index”) is the exclusive property of Indxx, LLC. Indxx, LLC uses its best efforts to ensure that the Index is calculated correctly. Indxx, LLC has no obligation to point out errors in the Index to third parties. Market Vectors Generic Drugs ETF is not sponsored, endorsed, sold or promoted by Indxx, LLC and Indxx, LLC makes no representation regarding the advisability of investing in Market Vectors Generic Drugs ETF.

Fund shares are not individually redeemable and will be issued and redeemed at their ”Net Asset Value” (NAV) only through certain authorized broker-dealers in large, specified blocks of shares called creation units and otherwise can be bought and sold only through exchange trading. Creation units are issued and redeemed principally in kind. Shares may trade at a premium or discount to their NAV in the secondary market.

Investing involves substantial risk and high volatility, including possible loss of principal. An investor should consider the investment objective, risks, charges and expenses of the Fund carefully before investing. To obtain a prospectus and summary prospectus, which contains this and other information call 800.826.2333 or visit http://www.vaneck.com/market-vectors. Please read the prospectus and summary prospectus carefully before investing.

Van Eck Securities Corporation
666 Third Avenue
New York, NY 10017
800.826.2333

This message is intended only for the personal and confidential use of the designated recipient. If you are not the intended recipient of this message you are hereby notified that any review, dissemination, distribution, or copying of this message is strictly prohibited. This communication is for informational purposes only and should not be regarded as an offer to sell or as a solicitation of an offer to buy any financial product, an official confirmation of any transaction, or as an official statement of Van Eck Global or any of its subsidiaries. Email transmissions cannot be guaranteed to be secure or error-free. Therefore we do not represent that this information is complete or accurate and it should not be relied upon as such. All information is subject to change without notice. All emails at Van Eck Global are, in accordance with Firm policy, to be used for Van Eck Global’s business purposes only. Emails sent from or to the Firm are subject to review by the Firm in accordance with the Firm’s procedure for the review of correspondence.

© Van Eck Global. All rights reserved

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Nya obligationsfonder från Amundi ger tillgång till eurostatsobligationer från europeiska länder

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Sedan i torsdags har tre nya börshandlade fonder utgivna av Amundi Asset Management kunnat handlas via Xetra och Börse Frankfurt. Dessa tre nya obligationsfonder från Amundi ger tillgång till eurostatsobligationer från europeiska länder.

Sedan i torsdags har tre nya börshandlade fonder utgivna av Amundi Asset Management kunnat handlas via Xetra och Börse Frankfurt. Dessa tre nya obligationsfonder från Amundi ger tillgång till eurostatsobligationer från europeiska länder.

Det nya Amundi Fixed Maturity-produktsortimentet investerar i en brett diversifierad portfölj av eurodenominerade statsobligationer som likvideras vid förfallodagen. Ränte- och amorteringsbetalningar från förfallande obligationer återinvesteras i statsobligationer utgivna av Frankrike och Tyskland med en återstående löptid på en månad till sex månader när som helst. Vid förfallodagen får investerarna det nominella värdet av obligationerna på en pro rata-basis och drar fördel av löpande räntebetalningar under denna tid.

Följande tre löptids-ETFer är tillgängliga:

Amundi Fixed Maturity 2028 Euro Government Bond Broad UCITS ETF (AK8E) investerar i statsobligationer emitterade av euroområdets medlemsländer med förfall 2028.

Amundi Fixed Maturity 2028 Euro Government Bond Yield+ UCITS ETF (AK8F) investerar i spanska, italienska och portugisiska statsobligationer med fast ränta som förfaller 2028.

Amundi Fixed Maturity 2027 German Bund Government Bond UCITS ETF (AK8G) investerar i tyska räntestatsobligationer som förfaller 2027.

NamnISINAvgiftUtdelnings-
policy
Referens-
index
Amundi Fixed Maturity 2028 Euro Government Bond Broad UCITS ETFLU27808714010,09 %UtdelandeFTSE Euro Broad Government 2028 Maturity Index
Amundi Fixed Maturity 2028 Euro Government Bond Yield+ UCITS ETFLU27808716660,09 %UtdelandeFTSE Euro Yield+ Government 2028 Maturity Index
Amundi Fixed Maturity 2027 German Bund Government Bond UCITS ETFLU27808718230,09 %UtdelandeFTSE German Government 2027 Maturity Index

Produktutbudet i Deutsche Börses XTF-segment omfattar för närvarande totalt 2 161 ETFer. Med detta urval och en genomsnittlig månatlig handelsvolym på cirka 14 miljarder euro är Xetra den ledande handelsplatsen för ETFer i Europa.

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Valour Chainlink (LINK) SEK ger exponering mot kryptovalutan LINK

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Valour Chainlink (LINK) SEK är en börshandlad produkt som spårar priset på LINK, den inhemska kryptovalutan i Chainlinks ekosystem.

Valour Chainlink (LINK) SEK är en börshandlad produkt som spårar priset på LINK, den inhemska kryptovalutan i Chainlinks ekosystem.

Chainlink är ett decentraliserat orakelnätverk som underlättar smarta kontrakt på blockchain-plattformar för att säkert ansluta till verkliga data, vilket möjliggör genomförandet av förtroendefria och manipuleringssäkra avtal. Det fungerar som en brygga mellan blockkedjebaserade smarta kontrakt och externa datakällor, vilket ger en pålitlig och decentraliserad lösning för att föra information utanför kedjan till blockkedjan.

Produktinformation

EmittentValour Inc.
NamnValour Chainlink (LINK) SEK
ISINCH1161139592
Valoren116113959
BasvalutaSEK
Underliggande tillgångCHAINLINK (LINK/USD)
FörfallodagOpen-Ended
Förvaltningskostnad1,9%

Handla Valour Chainlink (LINK)

Valour Chainlink (LINK) är en europeisk börshandlad produkt som handlas på bland annat Nordic Growth Market.

Det betyder att det går att handla andelar i denna ETP genom de flesta svenska banker och Internetmäklare, till exempel DEGIRONordnet, Aktieinvest och Avanza.

Börsnoteringar

BörsKortnamnValuta
Nordic Growth MarketVALOUR CHAINLINK (LINK) SEKSEK

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Bitcoin Warms up to Climate Goals and Ethereum’s Next Milestone: What Happened in Crypto This Week?

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Bitcoin Warms up to Climate Goals and Ethereum’s Next Milestone: What Happened in Crypto This Week? European Economy Booms while Regulators Consider Adopting Crypto

• European Economy Booms while Regulators Consider Adopting Crypto

• Bitcoin’s Growing Fundamentals and Institutionalization

• Ethereum’s Next Leap Forward: A Glimpse at the Upcoming Upgrade

European Economy Booms while Regulators Consider Adopting Crypto

Europe’s economy has exceeded expectations, with Germany’s gross domestic product (GDP) for Q1 2024 increasing by 0.2%, compared to the previous quarter’s reading of -0.5%. Additionally, France, Italy, and Spain are also seeing progress, picking up the bloc’s GDP from -0.1% to 0.3%. This is a good sign that Europe is on the right track away from a recession. Matching the positive outlook, regulators appear receptive to including new alternative assets within the EU’s most established regulatory framework.

Namely, the European Securities and Markets Authority (ESMA) is considering cryptoassets, among other asset classes like commodities and precious metals, in its Undertakings for Collective Investment in Transferable Securities (UCITS). Similar to mutual funds in the U.S., UCITS funds can be registered and sold in any country in the EU using unified regulatory and investor protection requirements. These funds are considered safe, well-regulated investments, hence their €12T market valuation and popularity among pension funds and risk-averse investors.

On May 7, ESMA invited investors and trade associations, among others, for a consultation to assess possible benefits and risks of UCITS gaining exposure to the selected 19 asset classes, having until August 7 to gather input. This is important since UCITS accounts for 75% of all collective retail investments in the EU. Thus, if the conclusions of this consultation are in favor of adopting crypto, it would attract an influx of investors and bring more regulated accessibility to this asset class. Moreover, although still under consultation, ESMA’s deliberation adds more credibility to crypto, considering the regulator’s renowned strict regulatory standards.

Further, the EU’s inflation is inching towards the 2% target, overshooting by only 0.4% in the past month, a level the U.S. is yet to achieve, with March’s inflation hitting 3.5%. Later today, a strong gauge for inflation is coming out, the Producer Price Index (PPI), measuring the change in the price of finished goods and services sold by producers. With the last consumer price index (CPI) disappointing, all eyes are on the CPI print coming out this Wednesday, along with data on retail sales. Although optimism seems to have checked out, a cooled inflation rate would recover investors’ appetite for risk-on assets like crypto, instigating more flows into Bitcoin spot ETFs, which have been especially quiet over the past week, as shown in Figure 1.

Figure 1: US Spot Bitcoin ETFs Flows

Source: Glassnode

Nevertheless, Bitcoin’s narrative has been growing beyond its primary use case as a store of value, with companies and governments alike leveraging Bitcoin mining to reduce their negative impact on the environment, ironically something Bitcoin is often scrutinized for.

Bitcoin’s Growing Fundamentals and Institutionalization

On May 7, Genesis Digital Assets and Argentina’s state-owned YPF Luz, the country’s largest producer of oil and gas with a ∼40% share in 2021, announced their opening of a Bitcoin mining facility. The data center takes ‘stranded gas,’ a byproduct of oil and gas production that would otherwise be flared and contribute to greenhouse gas emissions, to power the mining operation with the potential to reduce carbon dioxide equivalent emissions by 25-63%. Notably, 50 major oil and gas companies, representing over 40% of global petroleum production, signed the Oil and Gas Decarbonization Charter (OGDC), thereby committing to end gas flaring by 2030. The Argentinian project serves as a prime example of how companies can achieve the goals outlined in the OGDC, an approach likely to be replicated by others potentially using Bitcoin.

Aside from the obvious environmental benefits, projects like these actually strengthen Bitcoin’s network! More miners joining the fray means greater computing power, reflected by the growing hash rate in Figure 2. This results in a more secure network, as 51% attacks become more costly to execute successfully. The development comes at a crucial point in time, calming fears over miners exiting the network to cover costs, a dynamic often witnessed post-halving and one we explored in our Bitcoin Halving Report.

Figure 2 – Bitcoin Growing Hash Rate

Source: 21co on Dune

On a more familiar note, institutions continue to gobble up Bitcoin as an investment opportunity. The recent 13F filings mentioned last week revealed a growing appetite for Bitcoin as investment managers continue to disclose their U.S. equity holdings to the SEC. Quantitative trading firm Susquehanna holds over $1B in Bitcoin ETFs, with Boston-based hedge fund Bracebridge disclosing their $380M position too. Furthermore, in Japan, a weakened yen and government debt reaching 250% of GDP confirms sustained economic pressure, which has led early-stage investment firm Metaplanet to adopt Bitcoin as a strategic reserve. They have acquired over $7M since April, another testament to Bitcoin’s value proposition as a safe haven. The continuous adoption of Bitcoin is no surprise, given the accessibility of Bitcoin ETFs to traditional institutions through a regulated and familiar investment vehicle.

The positive Bitcoin sentiment is amplified by continuous innovation on the network itself. Bitcoin’s prime scaling solution, the Lightning Network, has taken a significant leap forward. By leveraging the Taproot Asset Upgrade, the Lightning Network successfully tested a protocol for issuing stablecoins directly on Bitcoin. This underscores the trend of Bitcoin’s growing use cases following the launch of Runes, which unlocked the ability to launch fungible tokens on Bitcoin. The recent surge in on-chain activity is reminiscent of the ERC-20 explosion in Ethereum’s early days, and stablecoins would truly unlock Bitcoin’s DeFi potential. They facilitate a wide range of transactions, shown below by Ethereum stablecoins amassing $3.8T in 2024 processed volume so far.

Figure 3 – Ethereum Stablecoin Volume

Source: 21co on Dune

While still in the early stages, this development would also significantly boost miner revenue, offering them a much-needed additional income stream through transaction fees, following the halving of block rewards last month. The potential of stablecoins on Bitcoin will be monitored going forward, as they have clear implications for the network’s potential on-chain footprint.

Ethereum’s Next Leap Forward: A Glimpse at the Upcoming Upgrade

More information is finally starting to come out regarding Ethereum’s next major upgrade, slated for late this year or early next year. Known as Pectra, the upgrade promises to introduce a range of enhancements aimed at bolstering the network’s stability and refining user experience. For example, the upgrade will raise the maximum stake per validator from 32 to 2,048 ETH, streamlining the management process for large validators who spread their stake across multiple wallets. Moreover, Pectra will tackle the problem of empty accounts, those with zero assets or funds, by removing them from the network. This action reduces the network’s state size, which effectively leads to lighter transaction processing.

Although the upgrade will incorporate various Ethereum Improvement Proposals (EIPs), one in particular stands out. Referred to as EIP 7702, Vitalik Buterin’s new proposal aims to expand upon the advancements made in Account Abstraction (AA) on Ethereum by refining certain concepts introduced in an earlier proposal, EIP 3074. As a quick recap, AA transforms users’ wallets, externally owned accounts (EOAs), into more sophisticated accounts resembling smart contracts, enhancing security, flexibility, and simplified user management. That said, EIP 7702 addresses some of EIP 3074 criticisms by steering clear of dependencies on EOA-specific functionalities. It aims to establish a versatile system capable of meeting the evolving needs of the Ethereum ecosystem while helping to reduce technical debt for the network

However, EIP 7702 proposes several other enhancements, including batched transactions, which could enhance transaction efficiency and even reduce fees by consolidating multiple user actions. Another exciting feature is the introduction of s sponsored transactions, which allow third-party applications to cover transaction fees for consumers, an ideal solution for onboarding new users. Finally, the upgrade could make users’ accounts resistant to threats from quantum computing. That said, with the proposal’s introduction of a new transaction type enabling EOAs to temporarily transition into smart accounts, concerns arise regarding the heightened risk of malicious actors’ ability to swiftly drain user wallets. Nevertheless, Vitalik’s proposal is intriguing as it charts a more pragmatic course toward realizing the AA vision. This is pivotal because it echoes our thesis at 21Shares that crypto won’t onboard millions of more users without providing them with an intuitive interface resembling the user-friendly experience they are familiar with across Web2.

Now, while Ethereum’s long-term prospects remain promising, its status as a deflationary network has come under threat in recent weeks, as seen below in Figure 3. This decline is primarily attributed to decreasing on-chain activity, which peaked at the end of March. Furthermore, the DenCun upgrade, implemented in March, significantly reduced the costs L2s incurred for storing their data on Ethereum by 90%.

Figure 4 – Ethereum’s Inflation

Source: 21co on Dune

It is worth noting that while it is currently more cost-effective for L2s to operate on Ethereum, these reduced costs will eventually onboard a larger user base. This will make it more feasible for applications, especially those requiring a high volume of interactions, to operate within the Ethereum ecosystem, which was previously economically unviable. A pivotal piece of evidence supporting this perspective is Arbitrum’s recent milestone, onboarding approximately 600K daily active users, as depicted in Figure 4. This likely influenced Securitize’s decision to propose deploying Blackrock’s BUIDL on Arbitrum, considering its position as the pioneering L2 platform with such a vibrant user base, alongside being the first L2 to process over $150B in swap volume on Uniswap, putting Arbitrum as the leading Ethereum scaling solution. Nevertheless, readers shouldn’t be wary, as we expect a broader spectrum of applications to arrive at the Ethereum network, helping to fill in the gap for Ethereum’s lost revenue while expanding the universe for what is possible within its ecosystem.

Figure 4 – Daily Active Users of Ethereum’s Leading Solutions

Source: GrowThePie

This Week’s Calendar

Source: Forex Factory, 21Shares

Research Newsletter

Each week the 21Shares Research team will publish our data-driven insights into the crypto asset world through this newsletter. Please direct any comments, questions, and words of feedback to research@21shares.com

Disclaimer

The information provided does not constitute a prospectus or other offering material and does not contain or constitute an offer to sell or a solicitation of any offer to buy securities in any jurisdiction. Some of the information published herein may contain forward-looking statements. Readers are cautioned that any such forward-looking statements are not guarantees of future performance and involve risks and uncertainties and that actual results may differ materially from those in the forward-looking statements as a result of various factors. The information contained herein may not be considered as economic, legal, tax or other advice and users are cautioned to base investment decisions or other decisions solely on the content hereof.

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